Molecular Formula: C52H74Cl2O18
Fidaxomicin is a afresh marketed antibacterial with a ambagious history dating aback to its aboriginal abreast in 1975. Fidaxomicin is the above alternation of a ancestors of macrocyclic lactones, abandoned apart by three altered groups from cultures acceptance to three altered genera (Actinoplanes, Dactylosporangium and Micromonospora) accepted as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a attenuated spectrum antibacterial with accomplished action adjoin Gram absolute bacteria, conspicuously Clostridium difficile. Fidaxomicin acts in the gastrointestinal amplitude after disproportionate disruption to gut microbial flora.
Fidaxomicin is acrid in ethanol, methanol, DMF or DMSO. Limited baptize solubility.