CAS NO. : 73384-59-5
Molecular formula: C18H18N8O7S3
Molecular weight: 554.58
Ceftriaxone is a broad-spectrum cephalosporin antibacterial with a actual continued half-life and top accuracy to meninges, eyes and close ears.
Ceftriaxone is a cephalosporin/cephamycin beta-lactam antibacterial acclimated in the analysis of bacterial infections acquired by susceptible, usually gram-positive, organisms. Ceftriaxone has in vitro action adjoin gram-positive and gram-negative aerobic and anaerobic bacteria. The antibacterial action of Ceftriaxone after-effects from the inhibition of cell bank amalgam and is advised through Ceftriaxone bounden to penicillin bounden proteins (PBPs). Ceftriaxone is abiding adjoin hydrolysis by a array of beta-lactamases, including penicillinases, and cephalosporinases and continued spectrum beta-lactamases.
Ceftriaxone works by inhibiting the mucopeptide amalgam in the bacterial cell wall. The beta-lactam atom of Ceftriaxone binds to carboxypeptidases, endopeptidases, and transpeptidases in the bacterial cytoplasmic membrane. These enzymes are complex in cell-wall amalgam and cell division. By bounden to these enzymes, Ceftriaxone after-effects in the accumulation of of abnormal cell walls and cell death.