What is α-ketoglutaric acid?

CAS No.: 328-50-7

Molecular Formula: C5H6O5

Molecular weight:146.10

α-Ketoglutaric acid is a keto acid of the Krebs aeon that is adapted to succinate through the activity of the thiamine pyrophosphate (TPP) -dependent enzyme, α-ketoglutarate dehydrogenase. α-Ketoglutaric acid is aswell affiliated to glutamic acid metabolism through the pyridoxal 5´-phosphate-dependent transamination reaction. The α-ketoglutarate:glutamate arrangement is about angled afterwards comestible vitamin B-6 restriction, suggesting that the arrangement may serve as a anatomic brand of vitamin B6 status.